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James W. Holsapple, MDChief, Department of Neurosurgery Professor and Chairman of Neurosurgery, Boston University School of Medicine Special Interests CV Highlights CV Highlights
Medical School Residencies Internship, General Surgery, Upstate Medical University (SUNY), Syracuse, NY (1987) Internship, Internal Medicine, St. Luke's Hospital, Kansas City, Missouri (1986) Postgraduate Training Visiting Fellow Functional Neurosurgery, Oregon Health Sciences University (2001) NRSA Research Fellow, Upstate Medical University and VAH Research Service, Departments of Neurosurgery and Physiology (1987-1990) Board Certification BiographyDr. James Holsapple, MD completed his medical education at the University of Kansas (1985). He completed internships in internal medicine (St. Luke's Hospital Kansas City Missouri) and general surgery (State University NY, Syracuse) and an NRSA supported research fellowship in neuroscience before beginning neurosurgical training at Upstate Medical University, Syracuse NY. Dr. Holsapple completed his neurosurgical training in 1994 and joined the neurosurgical faculty at UMU afterwards where he focused on general adult and pediatric neurosurgery. Dr. Holsapple initiated the functional neurosurgery/DBS program at UMU. He has maintained research interests in neuroscience collaborating in studies of primate vision and mechanisms of transmitter release. In 2009, Dr. Holsapple joined the faculty of the department of neurosurgery at Boston Medical Center where he continued his general practice in adult and pediatric neurosurgery. In October 2011, he was appointed chief and chair of Neurosurgery at Boston Medical Center and Boston University School of Medicine. PublicationsGorji R,Wang JP, Holsapple J,. and Eller, J. Hypothermic circulatory arrest for renal carcinoma.J Clin Anesth 2009;21:217-9. Holsapple, J.W. and Chin, L.S. Toward a Worldwide Standard: Neurosurgical Training in the U.S. and European Union. AANS Neurosurgeon Bulletin 2008 17(3). Doxtader, E.E., Butts, S.C., Holsapple, J.W. and Fuller, C.E. Aggressive pediatric meningioma with soft tissue and lymph node metastases: a case report. Pediatric and Developmental Pathology Caldicott, C.V. and Holsapple J. Training for Fitness: Reconsidering the 80-Hour Work Week. Perspectives in Biology and Medicine 51(1):134-43 (2008) John Hopkins. Motter, B.C. and Holsapple J. Saccades and Covert Shifts of Attention During Active Visual Search: Spatial distributions, memory and items per fixation. Vision Res, Vol. 47, No. 10. (May 2007), pp. 1261-1281. Darbar, A., Holsapple J., Krishnamurthy, S. and Hodge, C. Ventral Thoracic Cord Herniation: Frequently Misdiagnosed Entity. Spine 31(17):E600-5 (2006) Aug 1. K.V. Slavin and Holsapple J: Micro-electrode Techniques: Equipment, Components and Systems in micro-electrode recording in movement disorder surgery. Z. Israel and K. Burchiel Eds. Thieme New York. (2002) Lieberman, K., Wasenko, J., Holsapple J. and Rodziewicz, G.: Magnetic Resonance Imaging Characteristics of Hyperacute Hemorrhage in the Brain and Spine. Clinical Imaging 2002;26, 330-337. Kriebel, M.E., Fox, G.Q., Keller, B., Holsapple J. and Pappas, G.D.: The fusion pore array hypothesis of neurotransmitter secretion. The Neuroscientist (Vol 6, Number 6) Dec. 2000. Motter, B.C. and Holsapple J.W.: Cortical image density determines the probability of target discovery during active search. Vision Reasearch 40: 1311-1322, 2000. Motter, B.C. and Holsapple J.W.: Separating attention from chance in active visual search. In: Visual Attention and Neural Circuits, (Eds.) Braun, J, Koch, C. and Davis, J., MIT Press, 2000. Holsapple J.W.: Percutaneous balloon Compression of the Trigeminal Ganglion: Technique. In: Image Guided Pain Management, S. Thomas Editor, Lippincott-Raven (Philadelphia), 1997. Kriebel, M.E., Holsapple J., Keller, B., Pottlacher, G. and Bridy, D.: The periodic to chaotic water wheel. IUTAM Proceedings, In: Applications of non-linear and chaotic dynamics in mechanics, Ed. F. Moon, 1997. Wasenko, J.J., Hochhauser, L., Holsapple J.W., Poe, L.B., Albanese, S.A. and Cacyorin, E.D.: MR of post-traumatic spinal cord lesions: Unexpected improvement of hemorrhagic lesions. Clinical Imaging 21: 246-251, 1997. Wasenko, J.J., Holsapple JW., Winfield, J.A.: Cerebral venous thrombosis: Demonstration with magnetic resonance angiography. Clinical Imaging 19: 153-161, 1995. Vautrin, J., Kriebel, M. and Holsapple J.: Further evidence for the dynamic formation of transmitter quanta at the neuromuscular junction. Journal of Neuroscience Research 32: 245-254, 1992. Holsapple J.W., Preston, J.B. and Strick, P.L.: The origin of thalamic inputs to the 'hand" represention of the primary motor cortex. Journal of Neuroscience 11 (9) 2644-2654, 1991. Kriebel, M., Vautrin, J., and Holsapple J.: Transmitter release: Prepackaging and random mechanism or dynamic and deterministic process? Brain Research Reviews 15: 167-178, 1990. Holsapple J. and Brown, O.M.: Heart Acetylcholine Turnover: A mathematical model that predicts two pools. Pharmacologist 30 (3): 214, 1988. Cheney, P.D., Kasser, R. and Holsapple J.: Effects of DFP on the unit activity in rat superior colliculus. Brain Research 8:593-605, 1987. Welling, L., Welling, D.J., Holsapple J, and Evans, A.: Morphometric analysis of distinct microanatomy near the base of proximal tubule cells. American Journal of Physiology 253: 126-140, 1986. Cox, G.G., Rosenthal, S.J., and Holsapple J.W.:Exencephaly: Sonographic findings and radiologic-pathologic correlation. Radiology, 155: 755-756, 1985. Cheney, P.D., Kasser, R., and Holsapple J.: Reciprocal effect of single Corticomotoneuronal cells on wrist extensor and flexor muscle activity in the primate. Brain Research 247: 164-68, 1982.
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