Double balloon enteroscopy employs an endoscope with latex balloons attached at the tips that can be inflated and deflated with air from a pressure-controlled pump system. This technique can be performed using either an oral or anal route. Indications for double balloon enteroscopy include obscure gastrointestinal bleeding, Crohn's disease, unexplained diarrhea, but also pancreaticobiliary disease in patients with altered anatomy such as Roux-en-Y, access to the excluded stomach after bariatric surgery, and incomplete colonoscopy.