This is the most common cancer of the sinuses and adjacent skull base. The rapidly dividing cells which comprise the lining of the inner nose and sinuses degenerate into uncontrolled cancer in some people. This cancer is locally destructive. It can involve the sinuses, eyes, brain, and the roof of the mouth. It can extend deep into the cheek as well. In some cases, the lymph nodes of the neck can be involved or the cancer may spread further.